L-Citrulline Relation With Erectile Dysfunction

What Is Citrulline?

L-Citrulline for erectile dysfunction, l citrulline, erectile dysfunction

As I have already written a post on L-citrulline vs L-arginine and told that L-citrulline is an amino acid which is produced naturally by the human body and also found in foods, as such watermelon, nuts, leafy greens, legumes, dark chocolate, etc.

In fact, the body transforms L- citrulline into another amino acid called arginine, and also to nitric oxide. Most of the people take supplements of citrulline for heart health and erectile dysfunction, diabetes, weakness, high blood pressure, etc.

In fact, Citrulline is considered to work by increasing the supply of nitric oxide and the needs to produce a certain protein, and helps dilate blood vessels and to improve the fast blood circulation resulting in more oxygen, better pump, and a sufficient amount of nutrients supply into muscles.

Does L- Citrulline Help Erectile Dysfunction

However, apart from citrulline, arginine is also known to treat with erectile dysfunction, even though oral use of the amino acids results in comprehensive pre-systemic metabolism.

In fact, L-citrulline converts to arginine in your body and is not subjected to presystemic metabolism.

Hence, a team of researchers in Italy set up to test the safety and impact of citrulline supplements in improving erection hardness in men who had just mild erectile dysfunction (Study 1)

After the end of the study, they noted that the use of L-citrulline supplementation was less effective than taking any of the oral phosphodiesterase type 5 enzymes inhibitor for ED, for example, oral ED drugs as such Levitra, Cialis, and Viagra, the amino acid supplement has been proved to be good and safe by men with erectile dysfunction.

Dosage And Timing

As you know this, L-citrulline supplement is easily available over the counter. But few peer-reviewed studies have noticed the proper dosing for L-citrulline. However, there are no official dosing recommendations exist.

Though one study from the British Journal of Nutrition found the doses between 2-15 grams were tolerated and safe by men in that study.

But you don’t have to go high, and if I piratically talk about the doses. between 3-5 grams per day, and you can have 15-20 minutes before your workout and after too if needed.

When it comes to supplementing availability, range from 500 mg to 1.5g. However, some supplements contain a mixture of other ingredients and L-citrulline.

So, before you buy, read the supplement label first that how much amino acid you are purely getting with each dose. Always be a smart customer.


As per the research, the use of L-citrulline as erectile dysfunction (Ed) treatment is limited. Also, treatment with traditional ED medications as such the phosphodiesterase Viagra, Cialis, and Levitra has more proven to be effective.

However, a few men don’t prefer to use or rely on medications just because of side effects or possible risks.

It may be true especially for those who experience just only mid-ED., and in those cases, it may be preferable to use L-citrulline, out less for a short period of time.

On the other hand, L-citrulline is considered to be utterly safe, since studies have not found yet any bigger or known side effects.

Note– Before you any supplements in your life, if you are taking other medications, better would be to consult the doctor about possible interactions.

In fact, L-citrulline supplements may have extra synthetic ingredients equal to traditional erectile dysfunction. Remember, simultaneous use of citrulline supplements with additional drugs can lead to detrimental drops in your blood pressure.

Finally, this was the short and relevant answer to “L- citrulline” I hope you find it good. If you have any question regarding it feel free to share your thoughts below. Thanks.

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About Manish Upadhyay

My health paradise is committed to bringing some change and awareness in human life about Health and Fitness related info based on science. Here i will provide you about workouts tips, medical conditions, lifestyle and fitness news articles, much more. Stay tuned!

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4 Comments on “L-Citrulline Relation With Erectile Dysfunction”

  1. Hi! I’ve been reading your blog for a long time now and finally got the courage to go ahead and give you a shout out from Humble Tx! Just wanted to mention keep up the fantastic job!

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